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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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FAM110C
  • TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Family with sequence similarity 110, member C

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA036144
HPA036145

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Fractions of pancreatic cancers displayed strong cytoplasmic immunoreactivity while most colorectal cancers showed moderate staining. Remaining tumors were mainly negative.

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Several papillary adenocarcinomas of thyroid along with a few gliomas, lung, ovarian and stomach cancers displayed moderate cytoplasmic positivity. Occasional pancreatic cancers showed moderate to strong staining. Remaining cells were weakly stained or negative.

GENE INFORMATION

Gene name

FAM110C

Synonyms

Description

Family with sequence similarity 110, member C (HGNC Symbol)

Entrez gene summary

Chromosome

2

Cytoband

p25.3

Chromosome location (bp)

38814 - 46870

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184731 (version 83.38)

Entrez gene

642273

UniProt

Q1W6H9 (UniProt - Evidence at protein level)

neXtProt

NX_Q1W6H9

Antibodypedia

FAM110C antibodies

PROTEIN BROWSER

FAM110C-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM110C-001
ENSP00000328347
ENST00000327669
Q1W6H9 [Direct mapping]
Protein FAM110C
Show all
Predicted intracellular proteins
Show all
GO:0000922 [spindle pole]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005815 [microtubule organizing center]
GO:0005874 [microtubule]
GO:0005938 [cell cortex]
GO:0030335 [positive regulation of cell migration]
GO:0043014 [alpha-tubulin binding]
GO:0051897 [positive regulation of protein kinase B signaling]
GO:0060491 [regulation of cell projection assembly]
Show all
321 aa
33.9 kDa
No 0

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The Human Protein Atlas project is funded
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