Cell atlas - TCEAL2 - The Human Protein Atlas

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TCEAL2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nuclear speckles

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	TCEAL2
Gene description	Transcription elongation factor A (SII)-like 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nuclear speckles. In addition localized to the cytosol.
RNA cell category	Group enriched (U-2 OS, SCLC-21H)
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear speckles (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA076317
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (U-2 OS, SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nuclear speckles. In addition localized to the cytosol.

Main location

Nuclear speckles (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA076317	SH-SY5Y	Nuclear speckles
	HPA076317	SH-SY5Y	Cytosol
	HPA076317	U-2 OS	Nuclear speckles
	HPA076317	U-2 OS	Cytosol

GENE INFORMATION
Gene name	TCEAL2 (HGNC Symbol)
Synonyms	my048, MY0876G05, WEX1
Description	Transcription elongation factor A (SII)-like 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	q22.1
Chromosome location (bp)	102125688 - 102127711
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184905 (version 83.38)
Entrez gene	140597
UniProt	Q9H3H9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H3H9
Antibodypedia	TCEAL2 antibodies

PROTEIN BROWSER

TCEAL2-001	TCEAL2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TCEAL2-001 ENSP00000332359 ENST00000329035	Q9H3H9 [Direct mapping] Transcription elongation factor A protein-like 2 Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0050699 [WW domain binding] Show all	227 aa 25.8 kDa	No	0
TCEAL2-201 ENSP00000361866 ENST00000372780	Q9H3H9 [Direct mapping] Transcription elongation factor A protein-like 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0050699 [WW domain binding] Show all	227 aa 25.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.