Expression of NT5C1B in cancer - Summary

CANCER ATLAS

Gene description

5'-nucleotidase, cytosolic IB

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA056683

GENE INFORMATION
Gene name	NT5C1B (HGNC Symbol)
Synonyms	AIRP, CN-IB
Description	5'-nucleotidase, cytosolic IB (HGNC Symbol)
Entrez gene summary	Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	p24.2
Chromosome location (bp)	18562872 - 18589572
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000185013 (version 83.38)
Entrez gene	93034
UniProt	Q96P26 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96P26
Antibodypedia	NT5C1B antibodies

PROTEIN BROWSER

NT5C1B-001	NT5C1B-002	NT5C1B-006	NT5C1B-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NT5C1B-001 ENSP00000305979 ENST00000304081	Q96P26 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006144 [purine nucleobase metabolic process] GO:0006195 [purine nucleotide catabolic process] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0016311 [dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0055086 [nucleobase-containing small molecule metabolic process] Show all	550 aa 61.9 kDa	No	0
NT5C1B-002 ENSP00000352904 ENST00000359846	Q96P26 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006144 [purine nucleobase metabolic process] GO:0006195 [purine nucleotide catabolic process] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0016311 [dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0055086 [nucleobase-containing small molecule metabolic process] Show all	610 aa 68.8 kDa	No	0
NT5C1B-006 ENSP00000390811 ENST00000418427	H7BZQ4 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Predicted intracellular proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0016311 [dephosphorylation] Show all	265 aa 29.6 kDa	No	0
NT5C1B-008 ENSP00000401656 ENST00000416783	C9JW75 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Predicted intracellular proteins Show all		206 aa 22.8 kDa	No	0