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L3MBTL1

GENERAL INFORMATION

Gene name

 L3MBTL1

Gene description

 L(3)mbt-like 1 (Drosophila)

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 L3MBTL1 (HGNC Symbol)

Synonyms

 dJ138B7.3, DKFZp586P1522, KIAA0681, L3MBTL, ZC2HC3

Description

 L(3)mbt-like 1 (Drosophila) (HGNC Symbol)

Entrez gene summary

 This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]

Chromosome

 20

Cytoband

 q13.12

Chromosome location (bp)

 43507680 - 43550950

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000185513 (version 83.38)

Entrez gene

 26013

UniProt

 Q9Y468 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y468

Antibodypedia

 L3MBTL1 antibodies

PROTEIN BROWSER
L3MBTL1-003
L3MBTL1-005
L3MBTL1-007
L3MBTL1-011
L3MBTL1-014
L3MBTL1-015
L3MBTL1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
L3MBTL1-003
ENSP00000362226
ENST00000373134
A0A0A0MRR4 [Direct mapping]
Lethal(3)malignant brain tumor-like protein 1
Show all
Predicted intracellular proteins
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
Show all
 743 aa
83 kDa 		No 0
L3MBTL1-005
ENSP00000362227
ENST00000373135
Q9Y468 [Direct mapping]
Lethal(3)malignant brain tumor-like protein 1
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000785 [chromatin]
GO:0000793 [condensed chromosome]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005886 [plasma membrane]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007088 [regulation of mitotic nuclear division]
GO:0008270 [zinc ion binding]
GO:0016568 [chromatin modification]
GO:0030097 [hemopoiesis]
GO:0031491 [nucleosome binding]
GO:0031493 [nucleosomal histone binding]
GO:0032093 [SAM domain binding]
GO:0035064 [methylated histone binding]
GO:0042393 [histone binding]
GO:0042802 [identical protein binding]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0051726 [regulation of cell cycle]
Show all
 772 aa
85.9 kDa 		No 0
L3MBTL1-007
ENSP00000402107
ENST00000427442
Q9Y468 [Direct mapping]
Lethal(3)malignant brain tumor-like protein 1
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000785 [chromatin]
GO:0000793 [condensed chromosome]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005886 [plasma membrane]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007088 [regulation of mitotic nuclear division]
GO:0008270 [zinc ion binding]
GO:0016568 [chromatin modification]
GO:0030097 [hemopoiesis]
GO:0031491 [nucleosome binding]
GO:0031493 [nucleosomal histone binding]
GO:0032093 [SAM domain binding]
GO:0035064 [methylated histone binding]
GO:0042393 [histone binding]
GO:0042802 [identical protein binding]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0051726 [regulation of cell cycle]
Show all
 840 aa
92.3 kDa 		No 0
L3MBTL1-011
ENSP00000410139
ENST00000422861
A0A0C4DG70 [Direct mapping]
Lethal(3)malignant brain tumor-like protein 1
Show all
Predicted intracellular proteins
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
Show all
 538 aa
60.5 kDa 		No 0
L3MBTL1-014
ENSP00000415971
ENST00000434666
B0QYN5 [Direct mapping]
Lethal(3)malignant brain tumor-like protein 1
Show all
Predicted intracellular proteins
Show all
 84 aa
8.6 kDa 		No 0
L3MBTL1-015
ENSP00000387971
ENST00000439769
B0QYN4 [Direct mapping]
Lethal(3)malignant brain tumor-like protein 1
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
 138 aa
14 kDa 		No 0
L3MBTL1-201
ENSP00000398516
ENST00000418998
Q9Y468 [Direct mapping]
Lethal(3)malignant brain tumor-like protein 1
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000785 [chromatin]
GO:0000793 [condensed chromosome]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005886 [plasma membrane]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007088 [regulation of mitotic nuclear division]
GO:0008270 [zinc ion binding]
GO:0016568 [chromatin modification]
GO:0030097 [hemopoiesis]
GO:0031491 [nucleosome binding]
GO:0031493 [nucleosomal histone binding]
GO:0032093 [SAM domain binding]
GO:0035064 [methylated histone binding]
GO:0042393 [histone binding]
GO:0042802 [identical protein binding]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0051726 [regulation of cell cycle]
Show all
 840 aa
92.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.