Tissue expression of KRT79 - Summary - The Human Protein Atlas

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KRT79

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	KRT79
Gene description	Keratin 79, type II
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (skin, breast)
GTEx:	Tissue enriched (skin)
FANTOM5:	Not detected

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression mainly in hair external root sheath, also expressed in squamous epithelial cells.

DATA RELIABILITY
Data reliability description	Presumed off target binding observed and disregarded.
Reliability score	Supported based on 1 antibody. HPA059347
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Hair

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (skin, breast)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (skin)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	KRT79 (HGNC Symbol)
Synonyms	K6L, KRT6L
Description	Keratin 79, type II (HGNC Symbol)
Entrez gene summary	Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
Chromosome	12
Cytoband	q13.13
Chromosome location (bp)	52821410 - 52834295
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185640 (version 83.38)
Entrez gene	338785
UniProt	Q5XKE5 (UniProt - Evidence at protein level)
neXtProt	NX_Q5XKE5
Antibodypedia	KRT79 antibodies

PROTEIN BROWSER

KRT79-001	KRT79-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRT79-001 ENSP00000328358 ENST00000330553	Q5XKE5 [Direct mapping] Keratin, type II cytoskeletal 79 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005515 [protein binding] GO:0005882 [intermediate filament] GO:0019899 [enzyme binding] GO:0045095 [keratin filament] GO:0070062 [extracellular exosome] Show all	535 aa 57.8 kDa	No	0
KRT79-003 ENSP00000449159 ENST00000549255	H0YID6 [Direct mapping] Keratin, type II cytoskeletal 79 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005882 [intermediate filament] Show all	119 aa 13.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.