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Several cases of breast and thyroid cancers showed weak to moderate nuclear staining. A few cases of malignant melanomas, colorectal and lung cancers exhibited moderate to strong cytoplasmic and/or membranous immunoreactivity. Remaining malignant cells were weakly stained or negative.
GENE INFORMATION
Gene name
LYG2 (HGNC Symbol)
Synonyms
LYGH
Description
Lysozyme G-like 2 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene contains a SLT domain, a protein domain present in bacterial lytic transglycosylase (SLT) and in eukaryotic lysozymes (GEWL). SLT domain catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyglucosamine (GlcNAc). [provided by RefSeq, Jul 2008]