Expression of CD300LF in cancer - Summary

CANCER ATLAS

Gene description

CD300 molecule-like family member f

Protein class

CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA013712

GENE INFORMATION
Gene name	CD300LF (HGNC Symbol)
Synonyms	CD300f, CLM1, IGSF13, IREM1, NKIR
Description	CD300 molecule-like family member f (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	74694311 - 74712978
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186074 (version 83.38)
Entrez gene	146722
UniProt	Q8TDQ1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TDQ1
Antibodypedia	CD300LF antibodies

PROTEIN BROWSER

CD300LF-001	CD300LF-002	CD300LF-003	CD300LF-005	CD300LF-006	CD300LF-007	CD300LF-201	CD300LF-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD300LF-001 ENSP00000327075 ENST00000326165	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	290 aa 32.3 kDa	Yes	1
CD300LF-002 ENSP00000463743 ENST00000469092	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	194 aa 21.4 kDa	No	0
CD300LF-003 ENSP00000464257 ENST00000464910	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	293 aa 32.6 kDa	No	1
CD300LF-005 ENSP00000464610 ENST00000581500	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	239 aa 26.5 kDa	No	1
CD300LF-006 ENSP00000462309 ENST00000583937	J3KS52 [Direct mapping] CMRF35-like molecule 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	305 aa 33.8 kDa	Yes	1
CD300LF-007 ENSP00000301573 ENST00000301573	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	244 aa 26.7 kDa	Yes	0
CD300LF-201 ENSP00000343751 ENST00000343125	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	194 aa 21.4 kDa	No	0
CD300LF-202 ENSP00000355294 ENST00000361254	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	239 aa 26.5 kDa	No	1