Expression of SMYD4 in cancer - Summary

CANCER ATLAS

Gene description

SET and MYND domain containing 4

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA030059

GENE INFORMATION
Gene name	SMYD4 (HGNC Symbol)
Synonyms	KIAA1936, ZMYND21
Description	SET and MYND domain containing 4 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.3
Chromosome location (bp)	1779485 - 1830634
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186532 (version 83.38)
Entrez gene	114826
UniProt	Q8IYR2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IYR2
Antibodypedia	SMYD4 antibodies

PROTEIN BROWSER

SMYD4-001	SMYD4-002	SMYD4-003	SMYD4-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SMYD4-001 ENSP00000304360 ENST00000305513	Q8IYR2 [Direct mapping] SET and MYND domain-containing protein 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008168 [methyltransferase activity] GO:0032259 [methylation] GO:0046872 [metal ion binding] Show all	804 aa 89.2 kDa	No	1
SMYD4-002 ENSP00000460921 ENST00000491788	I3L428 [Direct mapping] SET and MYND domain-containing protein 4 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	558 aa 61.5 kDa	No	0
SMYD4-003 ENSP00000461089 ENST00000571854	I3L496 [Direct mapping] SET and MYND domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		177 aa 20.1 kDa	No	0
SMYD4-005 ENSP00000459819 ENST00000570368	I3L2P4 [Direct mapping] SET and MYND domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		223 aa 25.3 kDa	No	0