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Several colorectal and few stomach cancers along with a single case each of duct carcinoma of breast and high grade urothelial cancer showed strong cytoplasmic immunoreactivity. Few prostate cancers were moderate to strongly stained. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
SELV
Synonyms
Description
Selenoprotein V (EntrezGene)
Entrez gene summary
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]