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LCE1A

GENERAL INFORMATION

Gene name

 LCE1A

Gene description

 Late cornified envelope 1A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skin)
GTEx:Tissue enriched (skin)

Protein evidence

 Evidence at transcript level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skin)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skin)

GENE INFORMATION

Gene name

 LCE1A (HGNC Symbol)

Synonyms

 LEP1

Description

 Late cornified envelope 1A (HGNC Symbol)

Entrez gene summary

 LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 [PubMed 15854049]). For further information on the LCE gene cluster, see GENE FAMILY below.[supplied by OMIM, Feb 2009]

Chromosome

 1

Cytoband

 q21.3

Chromosome location (bp)

 152827473 - 152827894

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000186844 (version 83.38)

Entrez gene

 353131

UniProt

 Q5T7P2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q5T7P2

Antibodypedia

 LCE1A antibodies

PROTEIN BROWSER
LCE1A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LCE1A-001
ENSP00000334869
ENST00000335123
Q5T7P2 [Direct mapping]
Late cornified envelope protein 1A
Show all
Predicted intracellular proteins
Show all
GO:0001533 [cornified envelope]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0008544 [epidermis development]
GO:0018149 [peptide cross-linking]
GO:0030216 [keratinocyte differentiation]
GO:0031424 [keratinization]
Show all
 110 aa
11 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.