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Prostate cancers along with few malignant gliomas, carcinoids, lung, breast, pancreatic and liver cancers exhibited moderate to strong cytoplasmic immunoreactivity seen in a granular or dot-like pattern. Remaining malignant tissues were negative.
GENE INFORMATION
Gene name
OR2AK2 (HGNC Symbol)
Synonyms
OR2AK1P
Description
Olfactory receptor, family 2, subfamily AK, member 2 (HGNC Symbol)
Entrez gene summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
