Expression of KRT12 in cancer - Summary

CANCER ATLAS

Gene description

Keratin 12, type I

Protein class

Disease related genes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA055217	HPA055835

GENE INFORMATION
Gene name	KRT12 (HGNC Symbol)
Synonyms	K12
Description	Keratin 12, type I (HGNC Symbol)
Entrez gene summary	KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	40861303 - 40867210
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187242 (version 83.38)
Entrez gene	3859
UniProt	Q99456 (UniProt - Evidence at protein level)
neXtProt	NX_Q99456
Antibodypedia	KRT12 antibodies

PROTEIN BROWSER

KRT12-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRT12-001 ENSP00000251643 ENST00000251643	Q99456 [Direct mapping] Keratin, type I cytoskeletal 12 Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005882 [intermediate filament] GO:0007601 [visual perception] GO:0060429 [epithelium development] GO:0061303 [cornea development in camera-type eye] GO:0070062 [extracellular exosome] Show all	494 aa 53.5 kDa	No	0