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Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
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GENE INFORMATION
Gene name
NPSR1 (HGNC Symbol)
Synonyms
GPR154, GPRA, PGR14
Description
Neuropeptide S receptor 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
