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Malignant cells in general displayed moderate nuclear immunoreactivity. Malignant lymphomas exhibited strong positivity in most cases. Renal and gastric cancers were in general weakly stained or negative.
GENE INFORMATION
Gene name
MAGEH1 (HGNC Symbol)
Synonyms
APR1
Description
Melanoma antigen family H1 (HGNC Symbol)
Entrez gene summary
This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway. [provided by RefSeq, Aug 2013]