Tissue expression of DHRS4L2 - Summary - The Human Protein Atlas

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DHRS4L2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	DHRS4L2
Gene description	Dehydrogenase/reductase (SDR family) member 4 like 2
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA023972
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	DHRS4L2 (HGNC Symbol)
Synonyms	SDR25C3
Description	Dehydrogenase/reductase (SDR family) member 4 like 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	23969874 - 24006408
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187630 (version 83.38)
Entrez gene	317749
UniProt	Q6PKH6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6PKH6
Antibodypedia	DHRS4L2 antibodies

PROTEIN BROWSER

DHRS4L2-001	DHRS4L2-003	DHRS4L2-004	DHRS4L2-005	DHRS4L2-006	DHRS4L2-008	DHRS4L2-009	DHRS4L2-201	DHRS4L2-202	DHRS4L2-203	DHRS4L2-204

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DHRS4L2-001 ENSP00000334801 ENST00000335125	Q6PKH6 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	232 aa 24.9 kDa	Yes	0
DHRS4L2-003 ENSP00000380261 ENST00000397071	E9PFL3 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	192 aa 20.9 kDa	No	0
DHRS4L2-004 ENSP00000453889 ENST00000559411	H0YN69 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	242 aa 25.8 kDa	No	0
DHRS4L2-005 ENSP00000439942 ENST00000537912	F6TD35 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	157 aa 17.1 kDa	No	0
DHRS4L2-006 ENSP00000453845 ENST00000558753	F6TD35 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	157 aa 17.1 kDa	No	0
DHRS4L2-008 ENSP00000453173 ENST00000559387	H0YLE1 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	49 aa 5.2 kDa	No	0
DHRS4L2-009 ENSP00000452875 ENST00000560276	H0YKN3 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	109 aa 11.6 kDa	No	0
DHRS4L2-201 ENSP00000372203 ENST00000382755	D3YTE6 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	276 aa 29.7 kDa	No	0
DHRS4L2-202 ENSP00000441095 ENST00000534993	F6VUV4 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	Predicted intracellular proteins Show all	GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	90 aa 9.8 kDa	No	0
DHRS4L2-203 ENSP00000441433 ENST00000543805	A0A087WSZ6 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	138 aa 15 kDa	No	0
DHRS4L2-204 ENSP00000481066 ENST00000621761	A0A087WXI8 [Direct mapping] Dehydrogenase/reductase SDR family member 4-like 2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	215 aa 23.2 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.