Expression of AMY1C in cancer - Summary

CANCER ATLAS

Gene description

Amylase, alpha 1C (salivary)

Protein class

Enzymes, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Pancreatic cancer

STAINING SUMMARY

HPA045394	HPA045399	HPA046980

GENE INFORMATION
Gene name	AMY1C (HGNC Symbol)
Synonyms	AMY1
Description	Amylase, alpha 1C (salivary) (HGNC Symbol)
Entrez gene summary	Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p21.1
Chromosome location (bp)	103750406 - 103758690
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187733 (version 83.38)
Entrez gene	278
UniProt	P04745 (UniProt - Evidence at protein level)
neXtProt	NX_P04745
Antibodypedia	AMY1C antibodies

PROTEIN BROWSER

AMY1C-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AMY1C-001 ENSP00000359096 ENST00000370079	P04745 [Direct mapping] Alpha-amylase 1 Show all	Enzymes ENZYME proteins Hydrolases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0003824 [catalytic activity] GO:0004556 [alpha-amylase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005975 [carbohydrate metabolic process] GO:0007586 [digestion] GO:0043169 [cation binding] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	511 aa 57.8 kDa	Yes	0