Expression of CYHR1 in cancer - Summary

CANCER ATLAS

Gene description

Cysteine/histidine-rich 1

Protein class

Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA053653

GENE INFORMATION
Gene name	CYHR1 (HGNC Symbol)
Synonyms	CHRP, KIAA0496, MGC13010
Description	Cysteine/histidine-rich 1 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q24.3
Chromosome location (bp)	144449582 - 144465677
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187954 (version 83.38)
Entrez gene	50626
UniProt	Q6ZMK1 (UniProt - Evidence at protein level)
neXtProt	NX_Q6ZMK1
Antibodypedia	CYHR1 antibodies

PROTEIN BROWSER

CYHR1-001	CYHR1-002	CYHR1-003	CYHR1-004	CYHR1-005	CYHR1-008	CYHR1-011	CYHR1-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CYHR1-001 ENSP00000387426 ENST00000438911	Q6ZMK1 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005635 [nuclear envelope] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0008270 [zinc ion binding] GO:0048471 [perinuclear region of cytoplasm] Show all	362 aa 40.7 kDa	Yes	0
CYHR1-002 ENSP00000433769 ENST00000530374	E9PJD7 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0008270 [zinc ion binding] Show all	404 aa 43.8 kDa	No	0
CYHR1-003 ENSP00000304826 ENST00000306145	Q6ZMK1 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0008270 [zinc ion binding] GO:0048471 [perinuclear region of cytoplasm] Show all	192 aa 19.9 kDa	Yes	3
CYHR1-004 ENSP00000414647 ENST00000424149	Q6ZMK1 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0008270 [zinc ion binding] GO:0048471 [perinuclear region of cytoplasm] Show all	192 aa 19.9 kDa	Yes	3
CYHR1-005 ENSP00000385962 ENST00000403000	Q6ZMK1 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0008270 [zinc ion binding] GO:0048471 [perinuclear region of cytoplasm] Show all	192 aa 19.9 kDa	Yes	3
CYHR1-008 ENSP00000434642 ENST00000530637	E9PPA8 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		42 aa 4.1 kDa	Yes	0
CYHR1-011 ENSP00000434470 ENST00000526887	E9PQ42 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0008270 [zinc ion binding] Show all	246 aa 28 kDa	Yes	0
CYHR1-012 ENSP00000432902 ENST00000533764	E9PN77 [Direct mapping] Cysteine and histidine-rich protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	144 aa 14.4 kDa	Yes	2