Fields »
ABOUT
HELP
BLOG
ARL4C

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 ARL4C

Gene description

 ADP-ribosylation factor-like 4C

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the plasma membrane. In addition localized to the cytosol.

RNA cell category

 Cell line enhanced (RPTEC TERT1, U-2197)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Plasma membrane (supported)

Additional location

 In addition localized to the Cytosol (supported)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA028927
SHOW MORE

ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RPTEC TERT1, U-2197)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the plasma membrane. In addition localized to the cytosol.

Main location

 Plasma membrane (supported)

Additional location

 Cytosol (supported)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA028927 A-431 Plasma membrane
HPA028927 U-2 OS Cytosol
HPA028927 U-251 MG Plasma membrane
Cytosol

GENE INFORMATION

Gene name

 ARL4C (HGNC Symbol)

Synonyms

 ARL7, LAK

Description

 ADP-ribosylation factor-like 4C (HGNC Symbol)

Entrez gene summary

 ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q37.1

Chromosome location (bp)

 234493041 - 234497053

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000188042 (version 83.38)

Entrez gene

 10123

UniProt

 P56559 (UniProt - Evidence at protein level)

neXtProt

 NX_P56559

Antibodypedia

 ARL4C antibodies

PROTEIN BROWSER
ARL4C-001
ARL4C-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARL4C-001
ENSP00000375057
ENST00000390645
P56559 [Direct mapping]
ADP-ribosylation factor-like protein 4C
A0A024R4C5 [Target identity:100%; Query identity:100%]
ADP-ribosylation factor-like 4C, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0030175 [filopodium]
GO:0032456 [endocytic recycling]
GO:0043014 [alpha-tubulin binding]
Show all
 192 aa
21.5 kDa 		No 0
ARL4C-002
ENSP00000339754
ENST00000339728
P56559 [Direct mapping]
ADP-ribosylation factor-like protein 4C
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0030175 [filopodium]
GO:0032456 [endocytic recycling]
GO:0043014 [alpha-tubulin binding]
Show all
 201 aa
22.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.