Expression of GPR21 in cancer - Summary

CANCER ATLAS

Gene description

G protein-coupled receptor 21

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041651

GENE INFORMATION
Gene name	GPR21
Synonyms
Description	G protein-coupled receptor 21 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q33.2
Chromosome location (bp)	123034527 - 123035696
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000188394 (version 83.38)
Entrez gene
UniProt	Q99679 (UniProt - Evidence at transcript level)
neXtProt	NX_Q99679
Antibodypedia	GPR21 antibodies

PROTEIN BROWSER

GPR21-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR21-001 ENSP00000362746 ENST00000373642	Q99679 [Direct mapping] Probable G-protein coupled receptor 21 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007606 [sensory perception of chemical stimulus] GO:0008227 [G-protein coupled amine receptor activity] GO:0010579 [positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0040018 [positive regulation of multicellular organism growth] GO:0042593 [glucose homeostasis] GO:0046627 [negative regulation of insulin receptor signaling pathway] Show all	349 aa 39.5 kDa	No	7