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CLN3

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GENERAL INFORMATION

Gene name

 CLN3

Gene description

 Ceroid-lipofuscinosis, neuronal 3

Protein class

 Disease related genes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 18
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 CLN3 (HGNC Symbol)

Synonyms

 BTS, JNCL

Description

 Ceroid-lipofuscinosis, neuronal 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p12.1

Chromosome location (bp)

 28477279 - 28495575

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000188603 (version 83.38)

Entrez gene

 1201

UniProt

 Q13286 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13286

Antibodypedia

 CLN3 antibodies

PROTEIN BROWSER
«
CLN3-001
CLN3-005
CLN3-006
CLN3-007
CLN3-008
CLN3-009
CLN3-012
CLN3-014
CLN3-017
CLN3-020
CLN3-027
CLN3-030
CLN3-031
CLN3-201
CLN3-202
CLN3-203
CLN3-204
CLN3-205
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CLN3-001
ENSP00000454229
ENST00000569430
Q13286 [Direct mapping]
Battenin
A0A024QZB8 [Target identity:100%; Query identity:100%]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 438 aa
47.6 kDa 		No 9
CLN3-005
ENSP00000455387
ENST00000567963
H3BPM8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 341 aa
36.3 kDa 		No 6
CLN3-006
ENSP00000329171
ENST00000333496
Q13286 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 414 aa
45.2 kDa 		No 9
CLN3-007
ENSP00000379014
ENST00000395653
B4DMY6 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 338 aa
37 kDa 		No 8
CLN3-008
ENSP00000350457
ENST00000357806
Q13286 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 339 aa
38 kDa 		No 6
CLN3-009
ENSP00000455603
ENST00000568558
H3BQ48 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 184 aa
20.7 kDa 		No 1
CLN3-012
ENSP00000350523
ENST00000357857
B4DFF3 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 384 aa
41.6 kDa 		No 8
CLN3-014
ENSP00000458015
ENST00000565778
O95090 [Direct mapping]
Battenin
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
Show all
 167 aa
18.5 kDa 		No 0
CLN3-017
ENSP00000454899
ENST00000568443
H3BNK7 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
Show all
 175 aa
18.9 kDa 		No 2
CLN3-020
ENSP00000456117
ENST00000565316
Q13286 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 421 aa
45.6 kDa 		No 8
CLN3-027
ENSP00000455365
ENST00000567804
H3BPL0 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 74 aa
8.2 kDa 		No 1
CLN3-030
ENSP00000456122
ENST00000565688
H3BR84 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 176 aa
18.3 kDa 		No 4
CLN3-031
ENSP00000457615
ENST00000561505
H3BUF8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 121 aa
12.5 kDa 		No 3
CLN3-201
ENSP00000347660
ENST00000355477
Q9UBD8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 181 aa
19.3 kDa 		No 3
CLN3-202
ENSP00000353073
ENST00000359984
O95086 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 336 aa
36.8 kDa 		No 7
CLN3-203
ENSP00000353116
ENST00000360019
Q13286 [Direct mapping]
Battenin
A0A024QZB8 [Target identity:100%; Query identity:100%]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 438 aa
47.6 kDa 		No 9
CLN3-204
ENSP00000486178
ENST00000628023
H3BRU8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 82 aa
9.1 kDa 		No 1
CLN3-205
ENSP00000486616
ENST00000631023
H3BPM8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
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GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
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 341 aa
36.3 kDa 		No 6

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.