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Cancer cells showed moderate cytoplasmic and membranous immunoreactivity. Strong immunoreactivity was observed in cholangiocarcinomas, colorectal and pancreatic cancers.
GENE INFORMATION
Gene name
NANOS1 (HGNC Symbol)
Synonyms
NOS1
Description
Nanos homolog 1 (Drosophila) (HGNC Symbol)
Entrez gene summary
This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in this gene are associated with spermatogenic impairment. [provided by RefSeq, Sep 2015]