Cell atlas - PTAR1 - The Human Protein Atlas

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PTAR1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS CUSTOM DATA

GENE/PROTEIN

Antibody validation

Dictionary
	Microtubule organizing center
	Rods & Rings

Human cell
	Centrosome
	Cytosol

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GENERAL INFORMATION
Gene name	PTAR1
Gene description	Protein prenyltransferase alpha subunit repeat containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the microtubule organizing center. In addition localized to the rods & rings.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Microtubule organizing center (approved)
Additional location	In addition localized to the Rods & Rings (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA021248
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the microtubule organizing center. In addition localized to the rods & rings.

Main location

Microtubule organizing center (approved)

Additional location

Rods & Rings (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA021248	A-431	Microtubule organizing center
	HPA021248	U-2 OS	Microtubule organizing center
	HPA021248	U-2 OS	Rods & Rings
	HPA021248	U-251 MG	Microtubule organizing center

CUSTOM DATA


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Thumbnail	Antibody	Cell line	Assay	Description
	HPA021248	U-2 OS	Image	U-2 OS cells were treated with Ribavirin to induce the formation of Rods & Rings. Co-localization shows that PTAR1 localizes to Rods & Rings as the staining overlaps with a marker for Rods & Rings.

GENE INFORMATION
Gene name	PTAR1
Synonyms
Description	Protein prenyltransferase alpha subunit repeat containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q21.12
Chromosome location (bp)	69709522 - 69759959
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188647 (version 83.38)
Entrez gene	375743
UniProt	Q7Z6K3 (UniProt - Evidence at protein level)
neXtProt	NX_Q7Z6K3
Antibodypedia	PTAR1 antibodies

PROTEIN BROWSER

PTAR1-001	PTAR1-002	PTAR1-004	PTAR1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PTAR1-001 ENSP00000366405 ENST00000377200	X6R9N0 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008318 [protein prenyltransferase activity] GO:0018342 [protein prenylation] Show all	350 aa 39.9 kDa	No	0
PTAR1-002 ENSP00000344299 ENST00000340434	Q7Z6K3 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008318 [protein prenyltransferase activity] GO:0018342 [protein prenylation] GO:1990234 [transferase complex] Show all	402 aa 46.4 kDa	No	0
PTAR1-004 ENSP00000440164 ENST00000472967	F5GXY1 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		29 aa 3.3 kDa	No	0
PTAR1-005 ENSP00000405943 ENST00000415701	J3KQP8 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008318 [protein prenyltransferase activity] GO:0018342 [protein prenylation] Show all	168 aa 19.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.