Tissue expression of IDO2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	IDO2
Gene description	Indoleamine 2,3-dioxygenase 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (placenta, liver)
GTEx:	Group enriched (liver, testis, thyroid gland)
FANTOM5:	Tissue enriched (placenta)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (placenta, liver)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (liver, testis, thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (placenta)

GENE INFORMATION
Gene name	IDO2 (HGNC Symbol)
Synonyms	INDOL1
Description	Indoleamine 2,3-dioxygenase 2 (HGNC Symbol)
Entrez gene summary	Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
Chromosome	8
Cytoband	p11.21
Chromosome location (bp)	39934614 - 40016391
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188676 (version 83.38)
Entrez gene	169355
UniProt	Q6ZQW0 (UniProt - Evidence at protein level)
neXtProt	NX_Q6ZQW0
Antibodypedia	IDO2 antibodies

PROTEIN BROWSER

IDO2-004	IDO2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IDO2-004 ENSP00000426447 ENST00000389060	Q6ZQW0 [Direct mapping] Indoleamine 2,3-dioxygenase 2 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all	GO:0002376 [immune system process] GO:0004833 [tryptophan 2,3-dioxygenase activity] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006569 [tryptophan catabolic process] GO:0019441 [tryptophan catabolic process to kynurenine] GO:0020037 [heme binding] GO:0033754 [indoleamine 2,3-dioxygenase activity] GO:0034641 [cellular nitrogen compound metabolic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process] Show all	407 aa 45.4 kDa	No	0
IDO2-201 ENSP00000443432 ENST00000502986	F5H5G0 [Direct mapping] Indoleamine 2,3-dioxygenase 2 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all	GO:0005737 [cytoplasm] GO:0020037 [heme binding] Show all	420 aa 47.1 kDa	No	0