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OSTN

CANCER ATLAS

Gene description

 Osteocrin

Protein class

 Predicted secreted proteins

Protein evidence

 Evidence at transcript level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Endometrial cancer

STAINING SUMMARY
HPA030878
CAB024997
CAB025649

Tissue

Cancer staining
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

 Strong granular cytoplasmic staining was observed in a few cases of colorectal, lung, urothelial, gastric, pancreatic and liver cancers. Remaining cancers were negative.

GENE INFORMATION

Gene name

 OSTN

Synonyms

Description

 Osteocrin (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 q28

Chromosome location (bp)

 191199241 - 191265615

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000188729 (version 83.38)

Entrez gene

 344901

UniProt

 P61366 (UniProt - Evidence at transcript level)

neXtProt

 NX_P61366

Antibodypedia

 OSTN antibodies

PROTEIN BROWSER
OSTN-001
OSTN-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
OSTN-001
ENSP00000342356
ENST00000339051
P61366 [Direct mapping]
Osteocrin
Show all
   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0001503 [ossification]
GO:0003416 [endochondral bone growth]
GO:0005102 [receptor binding]
GO:0005179 [hormone activity]
GO:0005615 [extracellular space]
GO:0007166 [cell surface receptor signaling pathway]
GO:0030154 [cell differentiation]
GO:0030828 [positive regulation of cGMP biosynthetic process]
GO:0045668 [negative regulation of osteoblast differentiation]
GO:0046325 [negative regulation of glucose import]
Show all
 133 aa
14.7 kDa 		Yes 0
OSTN-002
ENSP00000416576
ENST00000445281
C9JER6 [Direct mapping]
Osteocrin
Show all
   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
 111 aa
12.1 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.