Cell atlas - HMX2 - The Human Protein Atlas

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HMX2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	HMX2
Gene description	H6 family homeobox 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (REH)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (REH) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	HMX2 (HGNC Symbol)
Synonyms	NKX5-2
Description	H6 family homeobox 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]
Chromosome	10
Cytoband	q26.13
Chromosome location (bp)	123148122 - 123150672
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000188816 (version 83.38)
Entrez gene	3167
UniProt	A2RU54 (UniProt - Evidence at transcript level)
neXtProt	NX_A2RU54
Antibodypedia	HMX2 antibodies

PROTEIN BROWSER

HMX2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HMX2-001 ENSP00000341108 ENST00000339992	A2RU54 [Direct mapping] Homeobox protein HMX2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007420 [brain development] GO:0008284 [positive regulation of cell proliferation] GO:0030154 [cell differentiation] GO:0042472 [inner ear morphogenesis] GO:0043565 [sequence-specific DNA binding] GO:0048026 [positive regulation of mRNA splicing, via spliceosome] Show all	273 aa 29.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.