Cell atlas - GLRA4 - The Human Protein Atlas

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GLRA4

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GLRA4
Gene description	Glycine receptor, alpha 4
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (SCLC-21H)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GLRA4
Synonyms
Description	Glycine receptor, alpha 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which has a neurotransmitter-gated ion-channel ligand binding domain. The encoded protein is very similar to a mouse protein which is a subunit of the retinal glycine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Chromosome	X
Cytoband	q22.2
Chromosome location (bp)	103707224 - 103728655
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000188828 (version 83.38)
Entrez gene	441509
UniProt	Q5JXX5 (UniProt - Inferred from homology)
neXtProt	NX_Q5JXX5
Antibodypedia	GLRA4 antibodies

PROTEIN BROWSER

GLRA4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLRA4-001 ENSP00000361700 ENST00000372617	Q5JXX5 [Direct mapping] Glycine receptor subunit alpha-4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005230 [extracellular ligand-gated ion channel activity] GO:0005887 [integral component of plasma membrane] GO:0006810 [transport] GO:0006811 [ion transport] GO:0007218 [neuropeptide signaling pathway] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016594 [glycine binding] GO:0016934 [extracellular-glycine-gated chloride channel activity] GO:0022824 [transmitter-gated ion channel activity] GO:0030054 [cell junction] GO:0034707 [chloride channel complex] GO:0042391 [regulation of membrane potential] GO:0043005 [neuron projection] GO:0043200 [response to amino acid] GO:0045202 [synapse] GO:0045211 [postsynaptic membrane] GO:0050877 [neurological system process] GO:0060012 [synaptic transmission, glycinergic] GO:1902476 [chloride transmembrane transport] Show all	417 aa 47.7 kDa	Yes	3

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.