Expression of HACD4 in cancer - Summary

CANCER ATLAS

Gene description

3-hydroxyacyl-CoA dehydratase 4

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Urothelial cancer

STAINING SUMMARY

HPA058666

GENE INFORMATION
Gene name	HACD4 (HGNC Symbol)
Synonyms	Em:AL662879.1, PTPLAD2
Description	3-hydroxyacyl-CoA dehydratase 4 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p21.3
Chromosome location (bp)	20999515 - 21031636
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188921 (version 83.38)
Entrez gene	401494
UniProt	Q5VWC8 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VWC8
Antibodypedia	HACD4 antibodies

PROTEIN BROWSER

HACD4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HACD4-001 ENSP00000419503 ENST00000495827	Q5VWC8 [Direct mapping] Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 Show all	Enzymes ENZYME proteins Lyases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0018812 [3-hydroxyacyl-CoA dehydratase activity] GO:0019899 [enzyme binding] GO:0030497 [fatty acid elongation] GO:0042761 [very long-chain fatty acid biosynthetic process] Show all	232 aa 27.5 kDa	No	5