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Breast cancers along with several cases of malignant gliomas, malignant melanomas, hepatocellular carcinomas, renal and prostate cancers exhibited moderate to strong cytoplasmic positivity. A few cases of breast cancers showed strong nuclear staining. Remaining malignant cells were in general weakly stained or negative.
GENE INFORMATION
Gene name
APOD
Synonyms
Description
Apolipoprotein D (HGNC Symbol)
Entrez gene summary
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]