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A few hepatocellular carcinomas, colorectal, breast and endometrial cancers showed moderate cytoplasmic immunoreactivity, with a granular pattern. One case of carcinoid, squamous cell carcinoma of lung and pancreatic cancer showed strong positivity. Other cancers were weakly stained or negative.
Most cancer tissues showed moderate cytoplasmic staining with occasional membranous or nuclear positivity in few cases. Many thyroid cancers along with a few liver and lung cancers were strongly stained. Several gliomas, lymphomas, renal and testis cancers were weakly stained or negative.