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S100A13

CANCER ATLAS

Gene description

 S100 calcium binding protein A13

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA019592
CAB025494

GENE INFORMATION

Gene name

 S100A13

Synonyms

Description

 S100 calcium binding protein A13 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 q21.3

Chromosome location (bp)

 153618787 - 153631360

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000189171 (version 83.38)

Entrez gene

 6284

UniProt

 Q99584 (UniProt - Evidence at protein level)

neXtProt

 NX_Q99584

Antibodypedia

 S100A13 antibodies

PROTEIN BROWSER
S100A13-001
S100A13-201
S100A13-202
S100A13-203

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
S100A13-001
ENSP00000344822
ENST00000339556
Q99584 [Direct mapping]
Protein S100-A13
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0008289 [lipid binding]
GO:0017134 [fibroblast growth factor binding]
GO:0042629 [mast cell granule]
GO:0042803 [protein homodimerization activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043303 [mast cell degranulation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050663 [cytokine secretion]
GO:0050703 [interleukin-1 alpha secretion]
GO:0050786 [RAGE receptor binding]
GO:0070062 [extracellular exosome]
Show all
 98 aa
11.5 kDa 		No 0
S100A13-201
ENSP00000376398
ENST00000392622
Q99584 [Direct mapping]
Protein S100-A13
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0008289 [lipid binding]
GO:0017134 [fibroblast growth factor binding]
GO:0042629 [mast cell granule]
GO:0042803 [protein homodimerization activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043303 [mast cell degranulation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050663 [cytokine secretion]
GO:0050703 [interleukin-1 alpha secretion]
GO:0050786 [RAGE receptor binding]
GO:0070062 [extracellular exosome]
Show all
 98 aa
11.5 kDa 		No 0
S100A13-202
ENSP00000376399
ENST00000392623
Q99584 [Direct mapping]
Protein S100-A13
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0008289 [lipid binding]
GO:0017134 [fibroblast growth factor binding]
GO:0042629 [mast cell granule]
GO:0042803 [protein homodimerization activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043303 [mast cell degranulation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050663 [cytokine secretion]
GO:0050703 [interleukin-1 alpha secretion]
GO:0050786 [RAGE receptor binding]
GO:0070062 [extracellular exosome]
Show all
 98 aa
11.5 kDa 		No 0
S100A13-203
ENSP00000392767
ENST00000440685
Q99584 [Direct mapping]
Protein S100-A13
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0008284 [positive regulation of cell proliferation]
GO:0008289 [lipid binding]
GO:0008360 [regulation of cell shape]
GO:0017134 [fibroblast growth factor binding]
GO:0042629 [mast cell granule]
GO:0042803 [protein homodimerization activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043303 [mast cell degranulation]
GO:0046688 [response to copper ion]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050663 [cytokine secretion]
GO:0050703 [interleukin-1 alpha secretion]
GO:0050786 [RAGE receptor binding]
GO:0051602 [response to electrical stimulus]
GO:0070062 [extracellular exosome]
Show all
 98 aa
11.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.