Fields »
ABOUT
HELP
BLOG
KRT77

CANCER ATLAS

Gene description

 Keratin 77, type II

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA045934

GENE INFORMATION

Gene name

 KRT77 (HGNC Symbol)

Synonyms

 KRT1B

Description

 Keratin 77, type II (HGNC Symbol)

Entrez gene summary

 Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

Chromosome

 12

Cytoband

 q13.13

Chromosome location (bp)

 52689626 - 52703463

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000189182 (version 83.38)

Entrez gene

 374454

UniProt

 Q7Z794 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q7Z794

Antibodypedia

 KRT77 antibodies

PROTEIN BROWSER
KRT77-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KRT77-001
ENSP00000342710
ENST00000341809
Q7Z794 [Direct mapping]
Keratin, type II cytoskeletal 1b
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005198 [structural molecule activity]
GO:0005856 [cytoskeleton]
GO:0005882 [intermediate filament]
GO:0008150 [biological_process]
GO:0045095 [keratin filament]
GO:0070062 [extracellular exosome]
Show all
 578 aa
61.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.