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ZKSCAN3

CANCER ATLAS

Gene description

 Zinc finger with KRAB and SCAN domains 3

Protein class

 Predicted intracellular proteins, Transcription factors

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA009637

GENE INFORMATION

Gene name

 ZKSCAN3 (HGNC Symbol)

Synonyms

 ZF47, Zfp47, ZNF306, ZNF309, ZSCAN35

Description

 Zinc finger with KRAB and SCAN domains 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 p22.1

Chromosome location (bp)

 28349914 - 28369177

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000189298 (version 83.38)

Entrez gene

 80317

UniProt

 Q9BRR0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BRR0

Antibodypedia

 ZKSCAN3 antibodies

PROTEIN BROWSER
ZKSCAN3-001
ZKSCAN3-002
ZKSCAN3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZKSCAN3-001
ENSP00000366465
ENST00000377255
Q9BRR0 [Direct mapping]
Zinc finger protein with KRAB and SCAN domains 3
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006914 [autophagy]
GO:0007040 [lysosome organization]
GO:0010507 [negative regulation of autophagy]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000773 [negative regulation of cellular senescence]
Show all
 538 aa
60.6 kDa 		No 0
ZKSCAN3-002
ENSP00000341883
ENST00000341464
Q9BRR0 [Direct mapping]
Zinc finger protein with KRAB and SCAN domains 3
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006914 [autophagy]
GO:0007040 [lysosome organization]
GO:0010507 [negative regulation of autophagy]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000773 [negative regulation of cellular senescence]
Show all
 390 aa
43.8 kDa 		No 0
ZKSCAN3-201
ENSP00000252211
ENST00000252211
Q9BRR0 [Direct mapping]
Zinc finger protein with KRAB and SCAN domains 3
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006914 [autophagy]
GO:0007040 [lysosome organization]
GO:0010507 [negative regulation of autophagy]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000773 [negative regulation of cellular senescence]
Show all
 538 aa
60.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.