Cell atlas - SH2D5 - The Human Protein Atlas

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SH2D5

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	SH2D5
Gene description	SH2 domain containing 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Cell line enhanced (U-2 OS, A-431)
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA030182
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-2 OS, A-431) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA030182	A-431	Cytosol
	HPA030182	U-2 OS	Cytosol
	HPA030182	U-251 MG	Cytosol

GENE INFORMATION
Gene name	SH2D5
Synonyms
Description	SH2 domain containing 5 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.12
Chromosome location (bp)	20719732 - 20732837
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000189410 (version 83.38)
Entrez gene	400745
UniProt	Q6ZV89 (UniProt - Evidence at protein level)
neXtProt	NX_Q6ZV89
Antibodypedia	SH2D5 antibodies

PROTEIN BROWSER

SH2D5-001	SH2D5-003	SH2D5-004	SH2D5-005	SH2D5-006	SH2D5-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SH2D5-001 ENSP00000364171 ENST00000375031	Q6ZV89 [Direct mapping] SH2 domain-containing protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0014069 [postsynaptic density] GO:0030054 [cell junction] GO:0045211 [postsynaptic membrane] Show all	339 aa 37.4 kDa	No	0
SH2D5-003 ENSP00000406026 ENST00000444387	Q6ZV89 [Direct mapping] SH2 domain-containing protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0014069 [postsynaptic density] GO:0030054 [cell junction] GO:0045211 [postsynaptic membrane] Show all	423 aa 46.8 kDa	No	0
SH2D5-004 ENSP00000428153 ENST00000518294	E5RJW5 [Direct mapping] SH2 domain-containing protein 5 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	131 aa 14.7 kDa	No	0
SH2D5-005 ENSP00000408509 ENST00000447746	J3KQT6 [Direct mapping] SH2 domain-containing protein 5 Show all	Predicted intracellular proteins Show all		134 aa 14.8 kDa	No	0
SH2D5-006 ENSP00000428656 ENST00000517430	E5RGV2 [Direct mapping] SH2 domain-containing protein 5 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	126 aa 14.2 kDa	No	0
SH2D5-007 ENSP00000430115 ENST00000519434	E5RGJ3 [Direct mapping] SH2 domain-containing protein 5 Show all	Predicted intracellular proteins Show all		70 aa 7.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.