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Most malignant cells showed weak to moderate cytoplasmic immunoreactivity, malignant gliomas, several malignant melanomas and a few skin cancers were strongly stained.
The product of this gene belongs to the armadillo repeat-containing family of proteins, which interact with other proteins in a variety of cellular processes. The function of this family member is currently unknown. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]