Cell atlas - MAN2A2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MAN2A2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	MAN2A2
Gene description	Mannosidase, alpha, class 2A, member 2
Protein class	Enzymes Plasma proteins Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	12
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MAN2A2 (HGNC Symbol)
Synonyms	HsT19662, MANA2X
Description	Mannosidase, alpha, class 2A, member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q26.1
Chromosome location (bp)	90902218 - 90922584
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196547 (version 83.38)
Entrez gene	4122
UniProt	P49641 (UniProt - Evidence at transcript level)
neXtProt	NX_P49641
Antibodypedia	MAN2A2 antibodies

PROTEIN BROWSER

MAN2A2-001	MAN2A2-006	MAN2A2-009	MAN2A2-010	MAN2A2-011	MAN2A2-012	MAN2A2-016	MAN2A2-020	MAN2A2-021	MAN2A2-030	MAN2A2-032	MAN2A2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAN2A2-001 ENSP00000452948 ENST00000559717	P49641 [Direct mapping] Alpha-mannosidase 2x Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003824 [catalytic activity] GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds] GO:0004559 [alpha-mannosidase activity] GO:0004572 [mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity] GO:0005975 [carbohydrate metabolic process] GO:0006013 [mannose metabolic process] GO:0006491 [N-glycan processing] GO:0006517 [protein deglycosylation] GO:0008270 [zinc ion binding] GO:0015923 [mannosidase activity] GO:0016021 [integral component of membrane] GO:0016799 [hydrolase activity, hydrolyzing N-glycosyl compounds] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030246 [carbohydrate binding] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] Show all	1150 aa 130.5 kDa	No	1
MAN2A2-006 ENSP00000453140 ENST00000557865	H0YLB9 [Direct mapping] Alpha-mannosidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds] GO:0004559 [alpha-mannosidase activity] GO:0005975 [carbohydrate metabolic process] GO:0006013 [mannose metabolic process] GO:0008270 [zinc ion binding] GO:0015923 [mannosidase activity] GO:0030246 [carbohydrate binding] Show all	793 aa 89.8 kDa	No	0
MAN2A2-009 ENSP00000453740 ENST00000558290	H0YMU0 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	72 aa 8.3 kDa	No	1
MAN2A2-010 ENSP00000452691 ENST00000558853	H0YK77 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	50 aa 5.6 kDa	No	1
MAN2A2-011 ENSP00000453078 ENST00000559999	H0YL67 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	120 aa 13.5 kDa	No	1
MAN2A2-012 ENSP00000452897 ENST00000559132	H0YKQ2 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004559 [alpha-mannosidase activity] GO:0005975 [carbohydrate metabolic process] Show all	195 aa 22.3 kDa	No	0
MAN2A2-016 ENSP00000452928 ENST00000558171	H0YKT0 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds] GO:0005975 [carbohydrate metabolic process] GO:0006013 [mannose metabolic process] GO:0008270 [zinc ion binding] GO:0015923 [mannosidase activity] GO:0030246 [carbohydrate binding] Show all	264 aa 29.4 kDa	No	0
MAN2A2-020 ENSP00000453253 ENST00000560147	H0YLL4 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005975 [carbohydrate metabolic process] GO:0006013 [mannose metabolic process] GO:0015923 [mannosidase activity] GO:0030246 [carbohydrate binding] Show all	165 aa 18.6 kDa	No	0
MAN2A2-021 ENSP00000452866 ENST00000560616	H0YKM7 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds] GO:0005975 [carbohydrate metabolic process] GO:0006013 [mannose metabolic process] GO:0008270 [zinc ion binding] GO:0015923 [mannosidase activity] GO:0030246 [carbohydrate binding] Show all	330 aa 35.8 kDa	No	0
MAN2A2-030 ENSP00000453341 ENST00000557990	H0YLU3 [Direct mapping] Alpha-mannosidase 2x Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005975 [carbohydrate metabolic process] GO:0006013 [mannose metabolic process] GO:0015923 [mannosidase activity] GO:0030246 [carbohydrate binding] Show all	319 aa 35.6 kDa	No	0
MAN2A2-032 ENSP00000453956 ENST00000559965	H0YNC8 [Direct mapping] Alpha-mannosidase 2x Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	76 aa 8.7 kDa	No	1
MAN2A2-201 ENSP00000353655 ENST00000360468	P49641 [Direct mapping] Alpha-mannosidase 2x Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003824 [catalytic activity] GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds] GO:0004559 [alpha-mannosidase activity] GO:0004572 [mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity] GO:0005975 [carbohydrate metabolic process] GO:0006013 [mannose metabolic process] GO:0006491 [N-glycan processing] GO:0006517 [protein deglycosylation] GO:0008270 [zinc ion binding] GO:0015923 [mannosidase activity] GO:0016021 [integral component of membrane] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030246 [carbohydrate binding] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] Show all	1150 aa 130.5 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.