Cell atlas - ZKSCAN5 - The Human Protein Atlas

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ZKSCAN5

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Intermediate filaments

Human cell
	Intermediate Filaments

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GENERAL INFORMATION
Gene name	ZKSCAN5
Gene description	Zinc finger with KRAB and SCAN domains 5
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the intermediate filaments.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Intermediate filaments (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA003201
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the intermediate filaments.

Main location

Intermediate filaments (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA003201	RH-30	Intermediate filaments
	HPA003201	U-2 OS	Intermediate filaments	Intensity

GENE INFORMATION
Gene name	ZKSCAN5 (HGNC Symbol)
Synonyms	ZFP95, ZNF914, ZSCAN37
Description	Zinc finger with KRAB and SCAN domains 5 (HGNC Symbol)
Entrez gene summary	This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain. A similar protein in mouse is differentially expressed in spermatogenesis. Two alternatively spliced transcript variants differing only in the 5' UTR have been described. Additional variants have been found, but their full-length sequences have not been determined. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	99504651 - 99534700
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196652 (version 83.38)
Entrez gene	23660
UniProt	Q9Y2L8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2L8
Antibodypedia	ZKSCAN5 antibodies

PROTEIN BROWSER

ZKSCAN5-001	ZKSCAN5-004	ZKSCAN5-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZKSCAN5-001 ENSP00000377725 ENST00000394170	Q9Y2L8 [Direct mapping] Zinc finger protein with KRAB and SCAN domains 5 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	839 aa 96.9 kDa	No	0
ZKSCAN5-004 ENSP00000392104 ENST00000451158	Q9Y2L8 [Direct mapping] Zinc finger protein with KRAB and SCAN domains 5 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	839 aa 96.9 kDa	No	0
ZKSCAN5-005 ENSP00000322872 ENST00000326775	Q9Y2L8 [Direct mapping] Zinc finger protein with KRAB and SCAN domains 5 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	839 aa 96.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.