Cell atlas - ZNF33B - The Human Protein Atlas

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ZNF33B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Endoplasmic reticulum
	Nucleoli

Human cell
	Endoplasmic Reticulum
	Nucleoli

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GENERAL INFORMATION
Gene name	ZNF33B
Gene description	Zinc finger protein 33B
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoli & endoplasmic reticulum. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (uncertain), Endoplasmic reticulum (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA005538
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoli & endoplasmic reticulum. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoli (uncertain), Endoplasmic reticulum (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA005538	SH-SY5Y	Nucleoli
	HPA005538	SH-SY5Y	Endoplasmic reticulum
	HPA005538	U-2 OS	Nucleoli fibrillar center
	HPA005538	U-2 OS	Endoplasmic reticulum

GENE INFORMATION
Gene name	ZNF33B (HGNC Symbol)
Synonyms	KOX2, KOX31, ZNF11B
Description	Zinc finger protein 33B (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the zinc finger family of proteins. This gene shows decreased expression in cumulus cells derived from patients undergoing controlled ovarian stimulation. This gene is present in a gene cluster with several related zinc finger genes in the pericentromeric region of chromosome 10. Pseudogenes have been identified on chromosomes 7 and 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Chromosome	10
Cytoband	q11.21
Chromosome location (bp)	42574185 - 42638568
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196693 (version 83.38)
Entrez gene	7582
UniProt	Q06732 (UniProt - Evidence at protein level)
neXtProt	NX_Q06732
Antibodypedia	ZNF33B antibodies

PROTEIN BROWSER

ZNF33B-001	ZNF33B-002	ZNF33B-005	ZNF33B-007	ZNF33B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF33B-001 ENSP00000484085 ENST00000462075	A0A087X1D4 [Direct mapping] Zinc finger protein 33B Show all	Predicted intracellular proteins Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	36 aa 4.4 kDa	No	0
ZNF33B-002 ENSP00000480979 ENST00000465206	A0A087WXF4 [Direct mapping] Zinc finger protein 33B Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	93 aa 11.1 kDa	No	0
ZNF33B-005 ENSP00000479296 ENST00000493285	A0A087WVA3 [Direct mapping] Zinc finger protein 33B Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	90 aa 10.6 kDa	No	0
ZNF33B-007 ENSP00000352444 ENST00000359467	Q06732 [Direct mapping] Zinc finger protein 33B Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	778 aa 90.7 kDa	No	0
ZNF33B-201 ENSP00000481265 ENST00000613419	A0A087WXT3 [Direct mapping] Zinc finger protein 33B Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	778 aa 90.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.