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Solute carrier family 39 (zinc transporter), member 10 (HGNC Symbol)
Entrez gene summary
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0002903 [negative regulation of B cell apoptotic process] GO:0005385 [zinc ion transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0006882 [cellular zinc ion homeostasis] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030001 [metal ion transport] GO:0030890 [positive regulation of B cell proliferation] GO:0046873 [metal ion transmembrane transporter activity] GO:0050861 [positive regulation of B cell receptor signaling pathway] GO:0055085 [transmembrane transport] GO:0071578 [zinc II ion transmembrane import] GO:1903615 [positive regulation of protein tyrosine phosphatase activity]
