Cell atlas - MAFG - The Human Protein Atlas

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MAFG

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	MAFG
Gene description	V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MAFG (HGNC Symbol)
Synonyms	MGC13090, MGC20149
Description	V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G (HGNC Symbol)
Entrez gene summary	Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM, Mar 2010]
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	81918270 - 81927714
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197063 (version 83.38)
Entrez gene	4097
UniProt	O15525 (UniProt - Evidence at protein level)
neXtProt	NX_O15525
Antibodypedia	MAFG antibodies

PROTEIN BROWSER

MAFG-001	MAFG-002	MAFG-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAFG-001 ENSP00000350369 ENST00000357736	O15525 [Direct mapping] Transcription factor MafG A0A024R8X1 [Target identity:100%; Query identity:100%] HCG1991559, isoform CRA_f Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0001701 [in utero embryonic development] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007596 [blood coagulation] GO:0010628 [positive regulation of gene expression] GO:0030534 [adult behavior] GO:0030641 [regulation of cellular pH] GO:0042127 [regulation of cell proliferation] GO:0043565 [sequence-specific DNA binding] GO:0045604 [regulation of epidermal cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] Show all	162 aa 17.8 kDa	No	0
MAFG-002 ENSP00000376173 ENST00000392366	O15525 [Direct mapping] Transcription factor MafG A0A024R8X1 [Target identity:100%; Query identity:100%] HCG1991559, isoform CRA_f Show all	Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007596 [blood coagulation] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046982 [protein heterodimerization activity] Show all	162 aa 17.8 kDa	No	0
MAFG-003 ENSP00000459634 ENST00000574686	I3L2F8 [Direct mapping] Transcription factor MafG Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0043565 [sequence-specific DNA binding] Show all	98 aa 11.2 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.