Expression of SLC6A17 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 6 (neutral amino acid transporter), member 17

Protein class

Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA008044

GENE INFORMATION
Gene name	SLC6A17
Synonyms
Description	Solute carrier family 6 (neutral amino acid transporter), member 17 (HGNC Symbol)
Entrez gene summary	The SLC6 family of proteins, which includes SLC6A17, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	110150486 - 110202202
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197106 (version 83.38)
Entrez gene	388662
UniProt	Q9H1V8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H1V8
Antibodypedia	SLC6A17 antibodies

PROTEIN BROWSER

SLC6A17-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC6A17-001 ENSP00000330199 ENST00000331565	Q9H1V8 [Direct mapping] Sodium-dependent neutral amino acid transporter SLC6A17 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003333 [amino acid transmembrane transport] GO:0005328 [neurotransmitter:sodium symporter activity] GO:0005887 [integral component of plasma membrane] GO:0006836 [neurotransmitter transport] GO:0007420 [brain development] GO:0008021 [synaptic vesicle] GO:0015171 [amino acid transmembrane transporter activity] GO:0015804 [neutral amino acid transport] GO:0015816 [glycine transport] GO:0015820 [leucine transport] GO:0015824 [proline transport] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0030672 [synaptic vesicle membrane] GO:0032328 [alanine transport] Show all	727 aa 81 kDa	No	>9