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A few hepatocellular carcinomas, thyroid, ovarian and colorectal cancers displayed weak to moderate cytoplasmic and nuclear positivity. Remaining cancer cells were negative.
GENE INFORMATION
Gene name
SULT1A2 (HGNC Symbol)
Synonyms
HAST4, STP2
Description
Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (HGNC Symbol)
Entrez gene summary
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]