Fields »
ABOUT
HELP
BLOG
PIWIL2

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 PIWIL2

Gene description

 Piwi-like RNA-mediated gene silencing 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enriched (NTERA-2)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (NTERA-2)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 PIWIL2 (HGNC Symbol)

Synonyms

 CT80, FLJ10351, HILI, Mili

Description

 Piwi-like RNA-mediated gene silencing 2 (HGNC Symbol)

Entrez gene summary

 PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]

Chromosome

 8

Cytoband

 p21.3

Chromosome location (bp)

 22275297 - 22357563

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197181 (version 83.38)

Entrez gene

 55124

UniProt

 Q8TC59 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TC59

Antibodypedia

 PIWIL2 antibodies

PROTEIN BROWSER
PIWIL2-001
PIWIL2-002
PIWIL2-003
PIWIL2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PIWIL2-001
ENSP00000349208
ENST00000356766
Q8TC59 [Direct mapping]
Piwi-like protein 2
W0HK13 [Target identity:100%; Query identity:100%]
Piwi-like protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000966 [RNA 5'-end processing]
GO:0003676 [nucleic acid binding]
GO:0003729 [mRNA binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005844 [polysome]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0010370 [perinucleolar chromocenter]
GO:0010467 [gene expression]
GO:0030718 [germ-line stem cell population maintenance]
GO:0031047 [gene silencing by RNA]
GO:0033391 [chromatoid body]
GO:0034584 [piRNA binding]
GO:0034587 [piRNA metabolic process]
GO:0043046 [DNA methylation involved in gamete generation]
GO:0043186 [P granule]
GO:0045727 [positive regulation of translation]
GO:0048477 [oogenesis]
GO:0051321 [meiotic cell cycle]
GO:0060903 [positive regulation of meiosis I]
GO:0071442 [positive regulation of histone H3-K14 acetylation]
GO:0071546 [pi-body]
GO:0097433 [dense body]
GO:2000617 [positive regulation of histone H3-K9 acetylation]
Show all
 973 aa
109.8 kDa 		No 0
PIWIL2-002
ENSP00000428267
ENST00000521356
Q8TC59 [Direct mapping]
Piwi-like protein 2
Show all
Predicted intracellular proteins
Show all
GO:0000966 [RNA 5'-end processing]
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0010467 [gene expression]
GO:0030718 [germ-line stem cell population maintenance]
GO:0031047 [gene silencing by RNA]
GO:0033391 [chromatoid body]
GO:0034584 [piRNA binding]
GO:0034587 [piRNA metabolic process]
GO:0043046 [DNA methylation involved in gamete generation]
GO:0043186 [P granule]
GO:0045727 [positive regulation of translation]
GO:0048477 [oogenesis]
GO:0051321 [meiotic cell cycle]
GO:0071546 [pi-body]
Show all
 937 aa
105.8 kDa 		No 0
PIWIL2-003
ENSP00000406956
ENST00000454009
Q8TC59 [Direct mapping]
Piwi-like protein 2
W0HK13 [Target identity:100%; Query identity:100%]
Piwi-like protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000966 [RNA 5'-end processing]
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0010467 [gene expression]
GO:0030718 [germ-line stem cell population maintenance]
GO:0031047 [gene silencing by RNA]
GO:0033391 [chromatoid body]
GO:0034584 [piRNA binding]
GO:0034587 [piRNA metabolic process]
GO:0043046 [DNA methylation involved in gamete generation]
GO:0043186 [P granule]
GO:0045727 [positive regulation of translation]
GO:0048477 [oogenesis]
GO:0051321 [meiotic cell cycle]
GO:0071546 [pi-body]
Show all
 973 aa
109.8 kDa 		No 0
PIWIL2-201
ENSP00000478103
ENST00000611073
Q8TC59 [Direct mapping]
Piwi-like protein 2
Show all
Predicted intracellular proteins
Show all
GO:0000966 [RNA 5'-end processing]
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0010467 [gene expression]
GO:0030718 [germ-line stem cell population maintenance]
GO:0031047 [gene silencing by RNA]
GO:0033391 [chromatoid body]
GO:0034584 [piRNA binding]
GO:0034587 [piRNA metabolic process]
GO:0043046 [DNA methylation involved in gamete generation]
GO:0043186 [P granule]
GO:0045727 [positive regulation of translation]
GO:0048477 [oogenesis]
GO:0051321 [meiotic cell cycle]
GO:0071546 [pi-body]
Show all
 937 aa
105.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.