Expression of SLC2A7 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 2 (facilitated glucose transporter), member 7

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039931

GENE INFORMATION
Gene name	SLC2A7 (HGNC Symbol)
Synonyms	GLUT7
Description	Solute carrier family 2 (facilitated glucose transporter), member 7 (HGNC Symbol)
Entrez gene summary	SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Li et al., 2004). This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	p36.23
Chromosome location (bp)	9003300 - 9026345
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197241 (version 83.38)
Entrez gene	155184
UniProt	Q6PXP3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6PXP3
Antibodypedia	SLC2A7 antibodies

PROTEIN BROWSER

SLC2A7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC2A7-001 ENSP00000383698 ENST00000400906	Q6PXP3 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 7 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0022891 [substrate-specific transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	512 aa 55.7 kDa	No	>9