Tissue expression of FITM2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FITM2
Gene description	Fat storage-inducing transmembrane protein 2
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (heart muscle)
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	FITM2 (HGNC Symbol)
Synonyms	C20orf142, dJ881L22.2, FIT2
Description	Fat storage-inducing transmembrane protein 2 (HGNC Symbol)
Entrez gene summary	FIT2 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008]
Chromosome	20
Cytoband	q13.12
Chromosome location (bp)	44302838 - 44311169
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197296 (version 83.38)
Entrez gene	128486
UniProt	Q8N6M3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N6M3
Antibodypedia	FITM2 antibodies

PROTEIN BROWSER

FITM2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FITM2-001 ENSP00000380037 ENST00000396825	Q8N6M3 [Direct mapping] Fat storage-inducing transmembrane protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005739 [mitochondrion] GO:0005789 [endoplasmic reticulum membrane] GO:0007010 [cytoskeleton organization] GO:0008654 [phospholipid biosynthetic process] GO:0010866 [regulation of triglyceride biosynthetic process] GO:0010890 [positive regulation of sequestering of triglyceride] GO:0019915 [lipid storage] GO:0022604 [regulation of cell morphogenesis] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0030730 [sequestering of triglyceride] GO:0034389 [lipid particle organization] GO:0035356 [cellular triglyceride homeostasis] Show all	262 aa 29.9 kDa	No	5