Fields »
ABOUT
HELP
BLOG
MIB2

CANCER ATLAS

Gene description

 Mindbomb E3 ubiquitin protein ligase 2

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA068322

GENE INFORMATION

Gene name

 MIB2 (HGNC Symbol)

Synonyms

 FLJ39787, skeletrophin, ZZANK1, ZZZ5

Description

 Mindbomb E3 ubiquitin protein ligase 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p36.33

Chromosome location (bp)

 1615415 - 1630610

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197530 (version 83.38)

Entrez gene

 142678

UniProt

 Q96AX9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96AX9

Antibodypedia

 MIB2 antibodies

PROTEIN BROWSER
«
MIB2-001
MIB2-003
MIB2-006
MIB2-008
MIB2-014
MIB2-016
MIB2-019
MIB2-021
MIB2-022
MIB2-026
MIB2-028
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MIB2-001
ENSP00000348081
ENST00000355826
Q96AX9 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0004842 [ubiquitin-protein transferase activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007219 [Notch signaling pathway]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0046872 [metal ion binding]
Show all
 1056 aa
114.3 kDa 		No 0
MIB2-003
ENSP00000428264
ENST00000518681
Q96AX9 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0004842 [ubiquitin-protein transferase activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007219 [Notch signaling pathway]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0046872 [metal ion binding]
Show all
 1005 aa
108.9 kDa 		No 0
MIB2-006
ENSP00000367984
ENST00000378712
Q96AX9 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0004842 [ubiquitin-protein transferase activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007219 [Notch signaling pathway]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0046872 [metal ion binding]
Show all
 753 aa
82.1 kDa 		No 0
MIB2-008
ENSP00000367980
ENST00000378708
F2Z2L2 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0046872 [metal ion binding]
Show all
 919 aa
99.5 kDa 		No 0
MIB2-014
ENSP00000464106
ENST00000483015
J3QR95 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
Show all
 332 aa
34.8 kDa 		No 0
MIB2-016
ENSP00000426103
ENST00000505820
Q96AX9 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000151 [ubiquitin ligase complex]
GO:0003779 [actin binding]
GO:0004842 [ubiquitin-protein transferase activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0007219 [Notch signaling pathway]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0046872 [metal ion binding]
GO:0061630 [ubiquitin protein ligase activity]
Show all
 1070 aa
115.9 kDa 		No 0
MIB2-019
ENSP00000426128
ENST00000504599
E9PD12 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0046872 [metal ion binding]
Show all
 969 aa
105.1 kDa 		No 0
MIB2-021
ENSP00000427680
ENST00000514234
H0YAM8 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0046872 [metal ion binding]
Show all
 829 aa
89.7 kDa 		No 0
MIB2-022
ENSP00000428660
ENST00000520777
Q96AX9 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0004842 [ubiquitin-protein transferase activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0007219 [Notch signaling pathway]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0046872 [metal ion binding]
Show all
 1066 aa
115.4 kDa 		No 0
MIB2-026
ENSP00000426865
ENST00000510793
D6RE96 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0046872 [metal ion binding]
Show all
 175 aa
19.7 kDa 		No 0
MIB2-028
ENSP00000426603
ENST00000503789
D6RFJ2 [Direct mapping]
E3 ubiquitin-protein ligase MIB2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0046872 [metal ion binding]
Show all
 149 aa
16.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.