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RPE

GENERAL INFORMATION

Gene name

 RPE

Gene description

 Ribulose-5-phosphate-3-epimerase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 15
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Reliability score

 Approved based on 2 antibodies.
HPA036498 , HPA036499
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RPE

Synonyms

Description

 Ribulose-5-phosphate-3-epimerase (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q34

Chromosome location (bp)

 210002565 - 210022259

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197713 (version 83.38)

Entrez gene

 6120

UniProt

 Q96AT9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96AT9

Antibodypedia

 RPE antibodies

PROTEIN BROWSER
«
RPE-001
RPE-002
RPE-003
RPE-004
RPE-005
RPE-007
RPE-008
RPE-009
RPE-010
RPE-011
RPE-012
RPE-013
RPE-014
RPE-016
RPE-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPE-001
ENSP00000352401
ENST00000359429
Q96AT9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 228 aa
24.9 kDa 		No 0
RPE-002
ENSP00000394455
ENST00000454822
Q96AT9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 178 aa
19.5 kDa 		No 0
RPE-003
ENSP00000401838
ENST00000429921
Q96AT9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 178 aa
19.5 kDa 		No 0
RPE-004
ENSP00000411186
ENST00000435437
C9J9T0 [Direct mapping]
Ribulose-5-phosphate-3-epimerase, isoform CRA_a; Ribulose-phosphate 3-epimerase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0046872 [metal ion binding]
Show all
 191 aa
21 kDa 		No 0
RPE-005
ENSP00000389411
ENST00000411934
Q96AT9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 160 aa
17.6 kDa 		No 0
RPE-007
ENSP00000397674
ENST00000438265
E7ESZ6 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
Show all
 147 aa
16.3 kDa 		No 0
RPE-008
ENSP00000403808
ENST00000436630
Q96AT9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 178 aa
19.5 kDa 		No 0
RPE-009
ENSP00000412245
ENST00000453724
E9PBG9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
Show all
 94 aa
10.4 kDa 		No 0
RPE-010
ENSP00000386194
ENST00000408981
C9J6A7 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
Show all
 159 aa
17.4 kDa 		No 0
RPE-011
ENSP00000392279
ENST00000429907
C9IYE8 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
Show all
 141 aa
15.7 kDa 		No 0
RPE-012
ENSP00000400449
ENST00000452025
C9IZU8 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0046872 [metal ion binding]
Show all
 225 aa
24.9 kDa 		No 0
RPE-013
ENSP00000405695
ENST00000445268
C9J8S0 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
Show all
 157 aa
17.6 kDa 		No 0
RPE-014
ENSP00000416805
ENST00000441588
C9JCL8 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0044262 [cellular carbohydrate metabolic process]
Show all
 107 aa
12 kDa 		No 0
RPE-016
ENSP00000402061
ENST00000438204
Q96AT9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 160 aa
17.6 kDa 		No 0
RPE-201
ENSP00000346501
ENST00000354506
Q96AT9 [Direct mapping]
Ribulose-phosphate 3-epimerase
Show all
Enzymes
   ENZYME proteins
   Isomerase
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004750 [ribulose-phosphate 3-epimerase activity]
GO:0005829 [cytosol]
GO:0005975 [carbohydrate metabolic process]
GO:0006098 [pentose-phosphate shunt]
GO:0008152 [metabolic process]
GO:0009052 [pentose-phosphate shunt, non-oxidative branch]
GO:0016857 [racemase and epimerase activity, acting on carbohydrates and derivatives]
GO:0019323 [pentose catabolic process]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0044262 [cellular carbohydrate metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 199 aa
21.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.