Cell atlas - ZNF181 - The Human Protein Atlas

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ZNF181

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF181
Gene description	Zinc finger protein 181
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA062305
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus.

Main location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA062305	RH-30	Nucleus
	HPA062305	SiHa	Nucleus
	HPA062305	SiHa	Vesicles	Intensity
	HPA062305	U-2 OS	Nucleus
	HPA062305	U-2 OS	Nucleoli

GENE INFORMATION
Gene name	ZNF181 (HGNC Symbol)
Synonyms	HHZ181, MGC44316
Description	Zinc finger protein 181 (HGNC Symbol)
Entrez gene summary	Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.[supplied by OMIM, Jul 2003]
Chromosome	19
Cytoband	q13.11
Chromosome location (bp)	34734155 - 34745378
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197841 (version 83.38)
Entrez gene	339318
UniProt	Q2M3W8 (UniProt - Evidence at protein level)
neXtProt	NX_Q2M3W8
Antibodypedia	ZNF181 antibodies

PROTEIN BROWSER

ZNF181-001	ZNF181-002	ZNF181-003	ZNF181-005	ZNF181-006	ZNF181-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF181-001 ENSP00000376065 ENST00000392232	F8W889 [Direct mapping] Zinc finger protein 181 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	615 aa 70.5 kDa	No	0
ZNF181-002 ENSP00000420727 ENST00000492450	Q2M3W8 [Direct mapping] Zinc finger protein 181 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	571 aa 65.8 kDa	No	0
ZNF181-003 ENSP00000419435 ENST00000459757	Q2M3W8 [Direct mapping] Zinc finger protein 181 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	570 aa 65.8 kDa	No	0
ZNF181-005 ENSP00000472046 ENST00000599244	M0R1Q2 [Direct mapping] Zinc finger protein 181 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	75 aa 8.7 kDa	No	0
ZNF181-006 ENSP00000473016 ENST00000595708	M0R361 [Direct mapping] Zinc finger protein 181 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	144 aa 16.8 kDa	No	0
ZNF181-007 ENSP00000471063 ENST00000593781	M0R074 [Direct mapping] Zinc finger protein 181 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	111 aa 13.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.