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HMGN5

CANCER ATLAS

Gene description

 High mobility group nucleosome binding domain 5

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA000511

GENE INFORMATION

Gene name

 HMGN5 (HGNC Symbol)

Synonyms

 NSBP1

Description

 High mobility group nucleosome binding domain 5 (HGNC Symbol)

Entrez gene summary

 This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009]

Chromosome

 X

Cytoband

 q21.1

Chromosome location (bp)

 81113701 - 81201942

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000198157 (version 83.38)

Entrez gene

 79366

UniProt

 P82970 (UniProt - Evidence at protein level)

neXtProt

 NX_P82970

Antibodypedia

 HMGN5 antibodies

PROTEIN BROWSER
HMGN5-001
HMGN5-002
HMGN5-003
HMGN5-004
HMGN5-006
HMGN5-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HMGN5-001
ENSP00000350848
ENST00000358130
P82970 [Direct mapping]
High mobility group nucleosome-binding domain-containing protein 5
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin]
GO:0003682 [chromatin binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0008284 [positive regulation of cell proliferation]
GO:0010628 [positive regulation of gene expression]
GO:0016568 [chromatin modification]
GO:0031492 [nucleosomal DNA binding]
GO:0043066 [negative regulation of apoptotic process]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0044822 [poly(A) RNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0071157 [negative regulation of cell cycle arrest]
Show all
 282 aa
31.5 kDa 		No 0
HMGN5-002
ENSP00000413402
ENST00000436386
Q5JSK8 [Direct mapping]
High mobility group nucleosome-binding domain-containing protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin]
GO:0005634 [nucleus]
GO:0031492 [nucleosomal DNA binding]
Show all
 102 aa
11.4 kDa 		No 0
HMGN5-003
ENSP00000404810
ENST00000451455
Q5JSK7 [Direct mapping]
High mobility group nucleosome-binding domain-containing protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin]
GO:0005634 [nucleus]
GO:0031492 [nucleosomal DNA binding]
Show all
 89 aa
10 kDa 		No 0
HMGN5-004
ENSP00000408060
ENST00000447319
Q5JSK9 [Direct mapping]
High mobility group nucleosome-binding domain-containing protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0031492 [nucleosomal DNA binding]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 201 aa
22.4 kDa 		No 0
HMGN5-006
ENSP00000399626
ENST00000430960
Q5JSL0 [Direct mapping]
High mobility group nucleosome-binding domain-containing protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0031492 [nucleosomal DNA binding]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 148 aa
16.5 kDa 		No 0
HMGN5-007
ENSP00000362347
ENST00000373250
Q5JSK6 [Direct mapping]
High mobility group nucleosome-binding domain-containing protein 5
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   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0031492 [nucleosomal DNA binding]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 161 aa
18 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.