Cell atlas - ZNF334 - The Human Protein Atlas

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ZNF334

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleus

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF334
Gene description	Zinc finger protein 334
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus. In addition localized to the cytosol.
RNA cell category	Cell line enhanced (BEWO, AF22, SCLC-21H)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA050022
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (BEWO, AF22, SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus. In addition localized to the cytosol.

Main location

Nucleus (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA050022	Hep G2	Nucleus
	HPA050022	SH-SY5Y	Nucleus
	HPA050022	SH-SY5Y	Cytosol
	HPA050022	U-2 OS	Nucleoplasm
	HPA050022	U-2 OS	Cytosol

GENE INFORMATION
Gene name	ZNF334 (HGNC Symbol)
Synonyms	bA179N14.1
Description	Zinc finger protein 334 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Chromosome	20
Cytoband	q13.12
Chromosome location (bp)	46499630 - 46513559
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198185 (version 83.38)
Entrez gene	55713
UniProt	Q9HCZ1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9HCZ1
Antibodypedia	ZNF334 antibodies

PROTEIN BROWSER

ZNF334-001	ZNF334-002	ZNF334-003	ZNF334-004	ZNF334-005	ZNF334-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF334-001 ENSP00000255129 ENST00000347606	Q9HCZ1 [Direct mapping] Zinc finger protein 334 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	680 aa 79.6 kDa	No	0
ZNF334-002 ENSP00000402582 ENST00000457685	A0A0B4J1Y0 [Direct mapping] Zinc finger protein 334; Zinc finger protein 334, isoform CRA_b Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	642 aa 75 kDa	No	0
ZNF334-003 ENSP00000473194 ENST00000593880	Q8N3P8 [Direct mapping] Putative uncharacterized protein DKFZp572F2170; Zinc finger protein 334 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	703 aa 81.5 kDa	No	0
ZNF334-004 ENSP00000473164 ENST00000596323	M0R3E1 [Direct mapping] Zinc finger protein 334 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	173 aa 20 kDa	No	0
ZNF334-005 ENSP00000485779 ENST00000625284	A0A087X1P4 [Direct mapping] Zinc finger protein 334; Zinc finger protein 334, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	679 aa 79.5 kDa	No	0
ZNF334-201 ENSP00000484362 ENST00000615481	A0A087X1P4 [Direct mapping] Zinc finger protein 334; Zinc finger protein 334, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	679 aa 79.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.