Expression of SULT1C2 in cancer - Summary

CANCER ATLAS

Gene description

Sulfotransferase family, cytosolic, 1C, member 2

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA007190

GENE INFORMATION
Gene name	SULT1C2 (HGNC Symbol)
Synonyms	ST1C1, SULT1C1
Description	Sulfotransferase family, cytosolic, 1C, member 2 (HGNC Symbol)
Entrez gene summary	Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q12.3
Chromosome location (bp)	108288639 - 108309915
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198203 (version 83.38)
Entrez gene	6819
UniProt	O00338 (UniProt - Evidence at protein level)
neXtProt	NX_O00338
Antibodypedia	SULT1C2 antibodies

PROTEIN BROWSER

SULT1C2-001	SULT1C2-002	SULT1C2-004	SULT1C2-005	SULT1C2-007	SULT1C2-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SULT1C2-001 ENSP00000251481 ENST00000251481	O00338 [Direct mapping] Sulfotransferase 1C2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006805 [xenobiotic metabolic process] GO:0008146 [sulfotransferase activity] GO:0009308 [amine metabolic process] GO:0044281 [small molecule metabolic process] GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process] GO:0051923 [sulfation] GO:0070062 [extracellular exosome] Show all	296 aa 34.9 kDa	No	0
SULT1C2-002 ENSP00000319622 ENST00000326853	O00338 [Direct mapping] Sulfotransferase 1C2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006805 [xenobiotic metabolic process] GO:0008146 [sulfotransferase activity] GO:0009308 [amine metabolic process] GO:0044281 [small molecule metabolic process] GO:0050427 [3'-phosphoadenosine 5'-phosphosulfate metabolic process] GO:0051923 [sulfation] GO:0070062 [extracellular exosome] Show all	307 aa 35.9 kDa	No	0
SULT1C2-004 ENSP00000401996 ENST00000438339	C9JSR0 [Direct mapping] Sulfotransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] Show all	130 aa 14.6 kDa	No	0
SULT1C2-005 ENSP00000387054 ENST00000409880	B8ZZF7 [Direct mapping] Sulfotransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] Show all	259 aa 30.7 kDa	No	0
SULT1C2-007 ENSP00000399651 ENST00000437390	B4DLP0 [Direct mapping] Sulfotransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] Show all	310 aa 36.6 kDa	No	0
SULT1C2-009 ENSP00000387340 ENST00000409067	H7BZ17 [Direct mapping] Sulfotransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] Show all	226 aa 26.6 kDa	No	0